Bitcoin (BTC) recorded approximately $2.52 billion in negative net exchange outflows over the three days from September 22 to 24, 2026, marking the largest multi-day withdrawal of the cryptocurrency from major centralized exchanges since 2023. Binance accounted for the largest single share, with more than 13,800 BTC leaving the platform in one day, according to on-chain analytics platform CryptoQuant. Net outflows of this kind mean more Bitcoin left exchange wallets than entered them over the period, leaving fewer coins immediately available to trade on those venues.

$2.52 Billion Pulled From Major Exchanges in Three Days

Data highlighted by CryptoQuant analyst Amr Taha show that Bitcoin registered an estimated $2.52 billion in combined negative net flows across key exchanges during the three-day window. Withdrawals were broad-based, with Binance, Coinbase, Kraken, and Bitfinex all posting net outflows over the period. Netflow—the difference between Bitcoin deposited to and withdrawn from exchange wallets—is among the on-chain indicators analysts use to gauge whether holders are positioning coins for near-term sale or moving them into self-custody.

September 22 was the heaviest day, with the four exchanges recording combined net outflows of roughly $1.574 billion. Binance led at $1.19 billion, followed by Coinbase at $286 million, Kraken at $55 million, and Bitfinex at $43 million.

Outflows continued on September 23, totaling approximately $438 million: $178 million from Binance, $175 million from Coinbase, $50 million from Bitfinex, and $35 million from Kraken. On September 24, the combined total reached around $511 million, with Binance at $370 million, Bitfinex at $88 million, and Coinbase at $53 million.

Binance Posts Record Single-Day Outflow

Binance recorded its highest single-day net Bitcoin outflow since 2023. According to CryptoQuant analyst Darkfost, more than 13,800 BTC were net withdrawn from the platform in a single day, worth roughly $1.16 billion at Bitcoin's prevailing price of nearly $84,000.

As of September 25, 2026, Binance's BTC reserves had fallen by approximately 20,000 BTC to 685,000 BTC, down from around 705,000 BTC. The exchange's weekly average netflow also remained negative at roughly 2,000 BTC. Reserve levels at major venues are tracked closely because they represent the supply most readily available for sale on the open market.

Binance's outsized share reflects its position as the largest holder of exchange-accessible BTC, with an estimated 30% of such balances across major platforms. That gave its withdrawals significant weight in the broader $2.52 billion multi-exchange net outflow recorded from September 22 to 24.

Context for Bitcoin's Trajectory

Bitcoin has rallied about 45% from its July lows and reclaimed its previous May high near $82,000. The sustained exchange outflows point to a shrinking pool of sell-side supply, and the divergence between rising prices and declining exchange balances resembles the accumulation phases observed in earlier market cycles, a pattern that could support price stability or further upside if demand holds.

Even so, exchange outflows alone do not guarantee short-term gains. Bitcoin's direction will still depend on spot demand, ETF flows, macroeconomic conditions, and overall market liquidity. With Binance's weekly average netflow still negative at roughly 2,000 BTC, follow-up reserve and netflow data will show whether the multi-day withdrawal trend extends or eases in the days ahead.